This is a sad loss to the film industry, particularly the action genre. Tony Scott directed 26 films and produced dozens more. He's best remembered for movies such as Top Gun, Days of Thunder and more recently Unstoppable. He has worked with actors such as Tom Cruise, Brad Pitt, Robert de Niro and Denzel Washington, and has been nominated for an Emmy 5 times, winning one.
Personally I regard him as one of the best action movie directors ever, and The Last Boy Scout is still one of my top three action films ever made. He'll be missed by fans of action films, and remembered fondly by many who grew up watching his movies.